Anti-Synaptophysin - Purified

Antibody Details

Product Details

Reactivity Species

Human

Host Species

Mouse

Immunogen

Rat retina synaptosome

Product Concentration

0.5 mg/ml

Formulation

This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.

Storage and Handling

This purified antibody is stable when stored at 2-8°C. Do not freeze.

Country of Origin

USA

Shipping

Next Day 2-8°C

RRID

AB_2831737

Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity

Mouse Anti-Human Synaptophysin (Clone SVP-38) recognizes an epitope on Human Synaptophysin. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Background

Synaptophysin (SYP) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells. SYP mapped the SYP locus to Xp11.23-p11.22. Regionalization of the gene on the X chromosome was also done with hamster/human hybrid cells in which various portions of the human X chromosome were present. Protein function: Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity.

Antigen Details

Protein

Synaptophysin

PubMed

Synaptophysin

NCBI Gene Bank ID

PubMed Link

UniProt.org

Information on Uniprot.org

Research Area

Cell Biology

.

Neuroscience

Technical Protocols