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Mosunetuzumab Biosimilar - Research Grade Europäischer Partner

5.970,00 €
Zzgl. MwSt.
ArtNr ICH5026-50MG
Hersteller IchorBio
Menge 50mg
Kategorie
Typ Biosimilars
Applikationen FA
Specific against Human (Homo sapiens)
Isotype IgG1
Purity >95% by SDS-PAGE
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias BTCT4465A
Lieferbar
Specificity Detects human CD3/CD20. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Mosunetuzumab. This product is for research use only.
Manufacturers Product Category
Low endotoxin, biosimilar antibody, Bispecific
Isotype Information
Human IgG1
Purification method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background
ichorbio’s Mosunetuzumab biosimilar is a bispecific, humanized monoclonal antibody with potential antineoplastic activity. Anti-CD20/CD3 bispecific monoclonal antibody BTCT4465A contains two antigen-recognition sites: one for human CD3, a T-cell surface antigen, and one for human CD20, a tumor-associated antigen (TAA) that is exclusively expressed on B cells during most stages of B-cell development and is often overexpressed in B-cell malignancies. Upon administration, BTCT4465A binds to both T cells and CD20-expressing tumor B cells; this cross-links T cells to tumor cells, and may result in a potent cytotoxic T-lymphocyte (CTL) response against CD20-expressing tumor B cells.
Concentration
5mg/ml
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50mg
Lieferbar: In stock
Listenpreis: 5.970,00 €
Preis: 5.970,00 €
lieferbar

Lieferung vsl. bis 02.10.2025 

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