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Theralizumab Biosimilar - Research Grade

Theralizumab Biosimilar - Research Grade

3.755,00 €

Zzgl. MwSt.

ArtNr	ICH5023-50MG
Hersteller	IchorBio
Menge	50mg
Kategorie	Antibodies In Vivo Antibodies
Typ	Biosimilars
Applikationen	FA
Specific against	Human (Homo sapiens)
Isotype	IgG4
Purity	>95% by SDS-PAGE
Citations	Huang et al. A bispecific antibody AP203 targeting PD-L1 and CD137 exerts potent antitumor activity without toxicity. Journal of Translational Medicine
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	TGN1412, CD28-SuperMAB, TAB08
Lieferbar
Specificity	Detects human CD28. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Theralizumab. This product is for research use only.
Manufacturers Product Category	Low endotoxin, biosimilar antibody
Isotype Information	Human IgG4
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background	Theralizumab GN1412 is a humanised monoclonal antibody that not only binds to, but is a strong agonist for, the CD28 receptor of the immune system’s T cells. CD28 is the co-receptor for the T cell receptor; It binds to receptors on the interacting partner in the reaction through one of its ligands (B7 family). It was withdrawn from development after inducing severe inflammatory reactions as well as chronic organ failure in the first-in-human study by PAREXEL in London in March 2006.
Concentration	5mg/ml
Formulation	Sterile, preservative-free, solution in PBS. BSA and Azide free.
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Storage	This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Application Notes	This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50mg

Listenpreis: 3.755,00 €

Preis: 3.755,00 €

lieferbar

Lieferung vsl. bis 18.09.2025

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