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Anti-Mouse ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1) Europäischer Partner

ArtNr ICH1101-100MG
Hersteller IchorBio
Menge 100mg
Kategorie
Typ Antibody
Purity >95% by SDS-PAGE and HPLC
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Intercellular adhesion molecule 1, Icam1, MALA-2, MyD10, CD54
Lieferbar
Specificity Anti-ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1) recognizes the (Mr 95 kD) cell surface glycoprotein known as intracellular adhesion molecule ICAM-1. ICAM-1 is the receptor for LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18).
Manufacturers Product Category
Low Endotoxin, anti-mouse
Target Information
ICAM-1
Isotype Information
Rat IgG2a
Antigen Distribution
The CD54 antigen is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes. It has been demonstrated that ICAM-1 enhances T-cell activation.
Background
Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies
Immunogen
Purified Recombinant Mouse ICAM-1 (>98%)
Concentration
0.5 mg/ml
Formulation
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Aggregation
Aggregation level ≤ 5%
Storage
anti-ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Application Notes
Blocking: This antibody blocks the binding LFA-1 (CD11a/CD18) to ICAM-1. The antibody is suitable for studies of inflammation, lymphocyte differentiation, and lymphocyte activation. - Each investigator should determine their own optimal working dilution for specific applications.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100mg
Lieferbar: In stock
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Lieferung vsl. bis 07.08.2025 

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