LC3A polyclonal antibody

Q9H492(Human) Q91VR7(Mouse) Q6XVN8(Rat)

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.

Peptide affinity purified

LC3A polyclonal antibody detects endogenous levels of LC3A protein.

For research use only, not for use in diagnostic procedure.