CD10 Antibody

Recombinant Protein

1?Sato Y, et.al. Journal of Gastroenterology, 1996 Feb.31(1):12-7. 2?Inukai T, et.al. British Journal of Haematology, 1995, 89(3):623-6.

4311

Purified Mouse Monoclonal Antibody

Figure 1: Immunohistochemical analysis of paraffin-embedded human breast ductal myoepithelium (A) and lymph tissue (B), showing cytoplasmic (A) and membrane (B) localization using CD10 mouse mAb with DAB staining (A) and AEC staining (B).

1/200 - 1/1000

85514

CD10 is a 100kDa glycoprotein, also designated Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt’s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

Purified recombinant fragment of human CD-10 expressed in E. Coli.