Goat anti-ORL1 / LOX1 / LOXIN Antibody

Goat anti-ORL1 / LOX1 / LOXIN Antibody
Principle Name: ORL1 / LOX1 / LOXIN
Official Symbol: OLR1
All Name and Symbols: OLR1; oxidized low density lipoprotein (lectin-like) receptor 1; CLEC8A; LOX1; LOXIN; SCARE1; SLOX1; C-type lectin domain family 8 member A; OTTHUMP00000238950; OTTHUMP00000238954; OTTHUMP00000238955; OTTHUMP00000238958; hLOX-1; lectin-type oxidized LDL r
Accession Number(s): NP_002534.1; NP_001166103.1; NP_001166104.1
Peptide Sequence: DLKIQTVKDQPDEK, is from N Terminus
Human Gene ID(s): 4973
Non-Human GeneID(s):
Important Comments: This antibody is expected to recognize all reported isoforms (NP_002534.1; NP_001166103.1; NP_001166104.1).
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As: lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20C. Minimize freezing and thawing.
Applications: Pep ELISA, WB
Tested Species: Human
Peptide ELISA: antibody detection limit dilution 1 to 128000.
Western Blot: Approx 40kDa band observed in Human Liver lysates (calculated MW of 30.9kDa according to NP_002534.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Yoshida et al, Biochem J. 1998 Aug
Reference(s): Shi Y, Cosentino F, Camici GG, Akhmedov A, Vanhoutte PM, Tanner FC, Lüscher TF. Oxidized low-density lipoprotein activates p66Shc via lectin-like oxidized low-density lipoprotein receptor-1, protein kinase C-beta, and c-Jun N-terminal kinase kinase in human endothelial cells. Arterioscler Thromb Vasc Biol. 2011 Sep; 31(9):2090-7..PMID: 21817106