Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4) Antibody

CTLA4 Antibody is a Rabbit Polyclonal antibody against CTLA4. This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008].

Affinity purified.

P16410

CTLA4

Calculated MW: 6 kDa, 8 kDa, 19 kDa, 24 kDa
Observed MW: 33 kDa

No