Glutamate Decarboxylase 2 (GAD2) Antibody Pair

Glutamate Decarboxylase 2 (GAD2) Antibody Pair for use in Sandwich ELISA assay development. This antibody pair contains:

• Glutamate Decarboxylase 2 (GAD2) capture antibody,
• Glutamate Decarboxylase 2 (GAD2) biotin-conjugated detection antibody,
• Glutamate Decarboxylase 2 (GAD2) standard.

It is recommended to use this antibody pair with abx098958 Antibody Pair Support Kit (Sandwich Method). This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

P48320

GAD2

The capture and detection antibody both contain 0.1% sodium azide.

No